Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication

Alterations to the gut microbiome are associated with various neurological diseases, yet evidence of causality and identity of microbiome-derived compounds that mediate gut-brain axis interaction remain elusive. Here, we identify two previously unknown bacterial metabolites 3-methyl-4-(trimethylammo...

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Detalles Bibliográficos
Autores principales: Hulme, Heather, Meikle, Lynsey M., Strittmatter, Nicole, van der Hooft, Justin J. J., Swales, John, Bragg, Ryan A., Villar, Victor H., Ormsby, Michael J., Barnes, Stephanie, Brown, Sheila L., Dexter, Alex, Kamat, Maya T., Komen, Jasper C., Walker, Daniel, Milling, Simon, Osterweil, Emily K., MacDonald, Andrew S., Schofield, Chris J., Tardito, Saverio, Bunch, Josephine, Douce, Gillian, Edgar, Julia M., Edrada-Ebel, RuAngelie, Goodwin, Richard J. A., Burchmore, Richard, Wall, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065903/
https://www.ncbi.nlm.nih.gov/pubmed/32195337
http://dx.doi.org/10.1126/sciadv.aax6328

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