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Apoptosis of A549 cells by small interfering RNA targeting survivin delivery using poly-β-amino ester/guanidinylated O-carboxymethyl chitosan nanoparticles

Gene-based therapeutics has emerged as a promising approach for human cancer therapy. Among a variety of non-viral vectors, polymer vectors are particularly attractive due to their safety and multivalent groups on their surface. This study focuses on guanidinylated O-carboxymethyl chitosan (GOCMCS)...

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Detalles Bibliográficos
Autores principales: Tang, Yue, Liu, Yun, Xie, Yuwen, Chen, Jing, Dou, Yushun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066049/
https://www.ncbi.nlm.nih.gov/pubmed/32175024
http://dx.doi.org/10.1016/j.ajps.2018.09.009