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Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems

An increasing number of centers not necessarily equipped with biplane (BP) angiosuites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients. We assessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, radiation and contrast agent ex...

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Autores principales: Guenego, Adrien, Mosimann, Pascal J., Wintermark, Max, Heit, Jeremy J., Zuber, Kevin, Dobrocky, Tomas, Lotterie, Jean Albert, Nicholson, Patrick, Marcellus, David G., Olivot, Jean Marc, Gonzalez, Nestor, Blanc, Raphaël, Pereira, Vitor Mendes, Gralla, Jan, Kaesmacher, Johannes, Fahed, Robert, Piotin, Michel, Cognard, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066129/
https://www.ncbi.nlm.nih.gov/pubmed/32161286
http://dx.doi.org/10.1038/s41598-020-60851-4
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author Guenego, Adrien
Mosimann, Pascal J.
Wintermark, Max
Heit, Jeremy J.
Zuber, Kevin
Dobrocky, Tomas
Lotterie, Jean Albert
Nicholson, Patrick
Marcellus, David G.
Olivot, Jean Marc
Gonzalez, Nestor
Blanc, Raphaël
Pereira, Vitor Mendes
Gralla, Jan
Kaesmacher, Johannes
Fahed, Robert
Piotin, Michel
Cognard, Christophe
author_facet Guenego, Adrien
Mosimann, Pascal J.
Wintermark, Max
Heit, Jeremy J.
Zuber, Kevin
Dobrocky, Tomas
Lotterie, Jean Albert
Nicholson, Patrick
Marcellus, David G.
Olivot, Jean Marc
Gonzalez, Nestor
Blanc, Raphaël
Pereira, Vitor Mendes
Gralla, Jan
Kaesmacher, Johannes
Fahed, Robert
Piotin, Michel
Cognard, Christophe
author_sort Guenego, Adrien
collection PubMed
description An increasing number of centers not necessarily equipped with biplane (BP) angiosuites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients. We assessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, radiation and contrast agent exposure. Consecutive patients treated by MT in four high volume centers between January 2014 and May 2017 were included. Demographic and MT characteristics were assessed and compared between SP and BP. Of 906 patients treated by MT, 576 (64%) were handled on a BP system. After multivariate analysis, contrast load and fluoroscopy duration were significantly lower in the BP group [100vs200mL, relative effect 0.85 (CI: 0.79–0.92), p = 0.0002; 22 vs 27 min, relative effect 0.84 (CI: 0.76–0.93), p = 0.0008, respectively]. There was no difference in recanalization (modified Thrombolysis-In-Cerebral-Infarction 2b-3), good clinical outcome (modified Rankin Scale 0–2), complications rates, procedure duration or radiation exposure. A three-vessel diagnostic angiogram performed prior to MT led to a significant increase in procedure duration (15% increase, p = 0.05), radiation exposure (33% increase, p < 0.0001) and contrast load (125% increase, p < 0.0001). Mechanical neuro-thrombectomy seems equally safe and effective on a single or biplane angiography system despite increased contrast load and fluoroscopy duration on the former.
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spelling pubmed-70661292020-03-19 Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems Guenego, Adrien Mosimann, Pascal J. Wintermark, Max Heit, Jeremy J. Zuber, Kevin Dobrocky, Tomas Lotterie, Jean Albert Nicholson, Patrick Marcellus, David G. Olivot, Jean Marc Gonzalez, Nestor Blanc, Raphaël Pereira, Vitor Mendes Gralla, Jan Kaesmacher, Johannes Fahed, Robert Piotin, Michel Cognard, Christophe Sci Rep Article An increasing number of centers not necessarily equipped with biplane (BP) angiosuites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients. We assessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, radiation and contrast agent exposure. Consecutive patients treated by MT in four high volume centers between January 2014 and May 2017 were included. Demographic and MT characteristics were assessed and compared between SP and BP. Of 906 patients treated by MT, 576 (64%) were handled on a BP system. After multivariate analysis, contrast load and fluoroscopy duration were significantly lower in the BP group [100vs200mL, relative effect 0.85 (CI: 0.79–0.92), p = 0.0002; 22 vs 27 min, relative effect 0.84 (CI: 0.76–0.93), p = 0.0008, respectively]. There was no difference in recanalization (modified Thrombolysis-In-Cerebral-Infarction 2b-3), good clinical outcome (modified Rankin Scale 0–2), complications rates, procedure duration or radiation exposure. A three-vessel diagnostic angiogram performed prior to MT led to a significant increase in procedure duration (15% increase, p = 0.05), radiation exposure (33% increase, p < 0.0001) and contrast load (125% increase, p < 0.0001). Mechanical neuro-thrombectomy seems equally safe and effective on a single or biplane angiography system despite increased contrast load and fluoroscopy duration on the former. Nature Publishing Group UK 2020-03-11 /pmc/articles/PMC7066129/ /pubmed/32161286 http://dx.doi.org/10.1038/s41598-020-60851-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Guenego, Adrien
Mosimann, Pascal J.
Wintermark, Max
Heit, Jeremy J.
Zuber, Kevin
Dobrocky, Tomas
Lotterie, Jean Albert
Nicholson, Patrick
Marcellus, David G.
Olivot, Jean Marc
Gonzalez, Nestor
Blanc, Raphaël
Pereira, Vitor Mendes
Gralla, Jan
Kaesmacher, Johannes
Fahed, Robert
Piotin, Michel
Cognard, Christophe
Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
title Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
title_full Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
title_fullStr Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
title_full_unstemmed Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
title_short Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems
title_sort safety and effectiveness of neuro-thrombectomy on single compared to biplane angiography systems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066129/
https://www.ncbi.nlm.nih.gov/pubmed/32161286
http://dx.doi.org/10.1038/s41598-020-60851-4
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