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TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid
The tripartite-motif protein, TRIM5α, is an innate immune sensor that potently restricts retrovirus infection by binding to human immunodeficiency virus capsids. Higher-ordered oligomerization of this protein forms hexagonally patterned structures that wrap around the viral capsid, despite an anomal...
Autores principales: | Yu, Alvin, Skorupka, Katarzyna A., Pak, Alexander J., Ganser-Pornillos, Barbie K., Pornillos, Owen, Voth, Gregory A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066149/ https://www.ncbi.nlm.nih.gov/pubmed/32161265 http://dx.doi.org/10.1038/s41467-020-15106-1 |
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