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Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly

The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly expanding the known proteome at the lower end of the size distribution. Here, we show that the mitochondrial proteome, particularly the respiratory chain, is enriched for small proteins. Using a prediction and valida...

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Detalles Bibliográficos
Autores principales: Zhang, Shan, Reljić, Boris, Liang, Chao, Kerouanton, Baptiste, Francisco, Joel Celio, Peh, Jih Hou, Mary, Camille, Jagannathan, Narendra Suhas, Olexiouk, Volodimir, Tang, Claire, Fidelito, Gio, Nama, Srikanth, Cheng, Ruey-Kuang, Wee, Caroline Lei, Wang, Loo Chien, Duek Roggli, Paula, Sampath, Prabha, Lane, Lydie, Petretto, Enrico, Sobota, Radoslaw M., Jesuthasan, Suresh, Tucker-Kellogg, Lisa, Reversade, Bruno, Menschaert, Gerben, Sun, Lei, Stroud, David A., Ho, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066179/
https://www.ncbi.nlm.nih.gov/pubmed/32161263
http://dx.doi.org/10.1038/s41467-020-14999-2