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Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly
The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly expanding the known proteome at the lower end of the size distribution. Here, we show that the mitochondrial proteome, particularly the respiratory chain, is enriched for small proteins. Using a prediction and valida...
Autores principales: | Zhang, Shan, Reljić, Boris, Liang, Chao, Kerouanton, Baptiste, Francisco, Joel Celio, Peh, Jih Hou, Mary, Camille, Jagannathan, Narendra Suhas, Olexiouk, Volodimir, Tang, Claire, Fidelito, Gio, Nama, Srikanth, Cheng, Ruey-Kuang, Wee, Caroline Lei, Wang, Loo Chien, Duek Roggli, Paula, Sampath, Prabha, Lane, Lydie, Petretto, Enrico, Sobota, Radoslaw M., Jesuthasan, Suresh, Tucker-Kellogg, Lisa, Reversade, Bruno, Menschaert, Gerben, Sun, Lei, Stroud, David A., Ho, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066179/ https://www.ncbi.nlm.nih.gov/pubmed/32161263 http://dx.doi.org/10.1038/s41467-020-14999-2 |
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