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pHLIP(Var7)-P1AP suppresses tumor cell proliferation in MDA-MB-231 triple-negative breast cancer by targeting protease activated receptor 1

PURPOSE: Protease-activated receptor 1 (PAR1) is a signaling protein ubiquitously present on the surface of tumor cells, and its homologous protein fragment, PAR1-activating peptide (P1AP), can inhibit protein signal transduction of PAR1/G in tumor cells. pH (Low) insertion peptide (pHLIP) can targe...

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Detalles Bibliográficos
Autores principales:	Yu, MingMing, Chen, YueHua, Wang, ZhenGuang, Ding, XiaoDong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Preclinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066270/ https://www.ncbi.nlm.nih.gov/pubmed/32034579 http://dx.doi.org/10.1007/s10549-020-05560-2

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