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Clinical pharmacological study of dotinurad administered to male and female elderly or young subjects

BACKGROUND: Dotinurad is a novel selective urate reabsorption inhibitor (SURI) that selectively inhibits the reabsorption of uric acid in renal tubules and promotes the excretion of uric acid into urine. In this study, the effects of age and gender on the pharmacokinetics (PK), pharmacodynamics (PD)...

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Detalles Bibliográficos
Autores principales:	Nakatani, Hiroshi, Fushimi, Masahiko, Sasaki, Tomomitsu, Okui, Daisuke, Ohashi, Tetsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066278/ https://www.ncbi.nlm.nih.gov/pubmed/31889230 http://dx.doi.org/10.1007/s10157-019-01836-0

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