Cargando…
An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure
The development of an in vitro system in which human primordial germ cell-like cells (hPGCLCs) are generated from human pluripotent stem cells (hPSCs) has been invaluable to further our understanding of human primordial germ cell (hPGC) specification. However, the means to evaluate the next fundamen...
Autores principales: | Gell, Joanna J., Liu, Wanlu, Sosa, Enrique, Chialastri, Alex, Hancock, Grace, Tao, Yu, Wamaitha, Sissy E., Bower, Grace, Dey, Siddharth S., Clark, Amander T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066331/ https://www.ncbi.nlm.nih.gov/pubmed/32059791 http://dx.doi.org/10.1016/j.stemcr.2020.01.009 |
Ejemplares similares
-
Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23
por: Clark, Amander T., et al.
Publicado: (2017) -
Active DNA demethylation is required for complete imprint erasure in primordial germ cells
por: Kawasaki, Yuki, et al.
Publicado: (2014) -
Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors
por: Chen, Di, et al.
Publicado: (2019) -
FGFR3 is expressed by human primordial germ cells and is repressed after meiotic initiation to form primordial oocytes
por: Chitiashvili, Tsotne, et al.
Publicado: (2022) -
Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
por: Sosa, Enrique, et al.
Publicado: (2018)