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Transgenesis and Genome Editing of Mouse Spermatogonial Stem Cells by Lentivirus Pseudotyped with Sendai Virus F Protein

Spermatogonial stem cells (SSCs) serve as a resource for producing genetically modified animals. However, genetic manipulation of SSCs has met with limited success. Here, we show efficient gene transfer into SSCs via a lentivirus (FV-LV) using a fusion protein (F), a Sendai virus (SV) envelope prote...

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Detalles Bibliográficos
Autores principales: Shinohara, Takashi, Kanatsu-Shinohara, Mito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066332/
https://www.ncbi.nlm.nih.gov/pubmed/32160520
http://dx.doi.org/10.1016/j.stemcr.2020.02.001

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