Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma

Glioblastoma (GBM) is an aggressive cancer with a very poor prognosis. Generally viewed as weakly immunogenic, GBM responds poorly to current immunotherapies. To understand this problem more clearly we used a combination of natural killer (NK) cell functional assays together with gene and protein ex...

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Detalles Bibliográficos
Autores principales: Close, H. J., Stead, L. F., Nsengimana, J., Reilly, K. A., Droop, A., Wurdak, H., Mathew, R. K., Corns, R., Newton‐Bishop, J., Melcher, A. A., Short, S. C., Cook, G. P., Wilson, E. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066386/
https://www.ncbi.nlm.nih.gov/pubmed/31784984
http://dx.doi.org/10.1111/cei.13403

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