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Synthesis, Characterization, and In Vivo Evaluation of Desmethyl Anethole Trithione Phosphate Prodrug for Ameliorating Cerebral Ischemia-Reperfusion Injury in Rats

[Image: see text] Anethol trithione (ATT) has a wide range of physiological activities, but its use is limited due to its poor water solubility. To improve the solubility of ATT, we synthesized and characterized a novel phosphate prodrug (ATXP) relying on the availability of the hydroxy group in 5-(...

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Detalles Bibliográficos
Autores principales: Huang, Sheng, Dong, Renhan, Xu, Gaojie, Liu, Jin, Gao, Xiaofang, Yu, Siqi, Qie, Pengfan, Gou, Gang, Hu, Min, Wang, Yu, Peng, Jian, Guang, Bing, Xu, Ying, Yang, Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066653/
https://www.ncbi.nlm.nih.gov/pubmed/32175506
http://dx.doi.org/10.1021/acsomega.9b04129