CHOP: haplotype-aware path indexing in population graphs

The practical use of graph-based reference genomes depends on the ability to align reads to them. Performing substring queries to paths through these graphs lies at the core of this task. The combination of increasing pattern length and encoded variations inevitably leads to a combinatorial explosio...

Descripción completa

Detalles Bibliográficos
Autores principales: Mokveld, Tom, Linthorst, Jasper, Al-Ars, Zaid, Holstege, Henne, Reinders, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066762/
https://www.ncbi.nlm.nih.gov/pubmed/32160922
http://dx.doi.org/10.1186/s13059-020-01963-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066762/
https://www.ncbi.nlm.nih.gov/pubmed/32160922
http://dx.doi.org/10.1186/s13059-020-01963-y

Ejemplares similares