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FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data
BACKGROUND: Informatics tools to support the integration and subsequent interrogation of spatiotemporal data such as clinical data and environmental exposures data are lacking. Such tools are needed to support research in environmental health and any biomedical field that is challenged by the need f...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066811/ https://www.ncbi.nlm.nih.gov/pubmed/32160884 http://dx.doi.org/10.1186/s12911-020-1056-9 |
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author | Xu, Hao Cox, Steven Stillwell, Lisa Pfaff, Emily Champion, James Ahalt, Stanley C. Fecho, Karamarie |
author_facet | Xu, Hao Cox, Steven Stillwell, Lisa Pfaff, Emily Champion, James Ahalt, Stanley C. Fecho, Karamarie |
author_sort | Xu, Hao |
collection | PubMed |
description | BACKGROUND: Informatics tools to support the integration and subsequent interrogation of spatiotemporal data such as clinical data and environmental exposures data are lacking. Such tools are needed to support research in environmental health and any biomedical field that is challenged by the need for integrated spatiotemporal data to examine individual-level determinants of health and disease. RESULTS: We have developed an open-source software application—FHIR PIT (Health Level 7 Fast Healthcare Interoperability Resources Patient data Integration Tool)—to enable studies on the impact of individual-level environmental exposures on health and disease. FHIR PIT was motivated by the need to integrate patient data derived from our institution’s clinical warehouse with a variety of public data sources on environmental exposures and then openly expose the data via ICEES (Integrated Clinical and Environmental Exposures Service). FHIR PIT consists of transformation steps or building blocks that can be chained together to form a transformation and integration workflow. Several transformation steps are generic and thus can be reused. As such, new types of data can be incorporated into the modular FHIR PIT pipeline by simply reusing generic steps or adding new ones. We validated FHIR PIT in the context of a driving use case designed to investigate the impact of airborne pollutant exposures on asthma. Specifically, we replicated published findings demonstrating racial disparities in the impact of airborne pollutants on asthma exacerbations. CONCLUSIONS: While FHIR PIT was developed to support our driving use case on asthma, the software can be used to integrate any type and number of spatiotemporal data sources at a level of granularity that enables individual-level study. We expect FHIR PIT to facilitate research in environmental health and numerous other biomedical disciplines. |
format | Online Article Text |
id | pubmed-7066811 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-70668112020-03-18 FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data Xu, Hao Cox, Steven Stillwell, Lisa Pfaff, Emily Champion, James Ahalt, Stanley C. Fecho, Karamarie BMC Med Inform Decis Mak Software BACKGROUND: Informatics tools to support the integration and subsequent interrogation of spatiotemporal data such as clinical data and environmental exposures data are lacking. Such tools are needed to support research in environmental health and any biomedical field that is challenged by the need for integrated spatiotemporal data to examine individual-level determinants of health and disease. RESULTS: We have developed an open-source software application—FHIR PIT (Health Level 7 Fast Healthcare Interoperability Resources Patient data Integration Tool)—to enable studies on the impact of individual-level environmental exposures on health and disease. FHIR PIT was motivated by the need to integrate patient data derived from our institution’s clinical warehouse with a variety of public data sources on environmental exposures and then openly expose the data via ICEES (Integrated Clinical and Environmental Exposures Service). FHIR PIT consists of transformation steps or building blocks that can be chained together to form a transformation and integration workflow. Several transformation steps are generic and thus can be reused. As such, new types of data can be incorporated into the modular FHIR PIT pipeline by simply reusing generic steps or adding new ones. We validated FHIR PIT in the context of a driving use case designed to investigate the impact of airborne pollutant exposures on asthma. Specifically, we replicated published findings demonstrating racial disparities in the impact of airborne pollutants on asthma exacerbations. CONCLUSIONS: While FHIR PIT was developed to support our driving use case on asthma, the software can be used to integrate any type and number of spatiotemporal data sources at a level of granularity that enables individual-level study. We expect FHIR PIT to facilitate research in environmental health and numerous other biomedical disciplines. BioMed Central 2020-03-11 /pmc/articles/PMC7066811/ /pubmed/32160884 http://dx.doi.org/10.1186/s12911-020-1056-9 Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Software Xu, Hao Cox, Steven Stillwell, Lisa Pfaff, Emily Champion, James Ahalt, Stanley C. Fecho, Karamarie FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
title | FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
title_full | FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
title_fullStr | FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
title_full_unstemmed | FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
title_short | FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
title_sort | fhir pit: an open software application for spatiotemporal integration of clinical data and environmental exposures data |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066811/ https://www.ncbi.nlm.nih.gov/pubmed/32160884 http://dx.doi.org/10.1186/s12911-020-1056-9 |
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