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Berberine promotes XIAP-mediated cells apoptosis by upregulation of miR-24-3p in acute lymphoblastic leukemia

Background: Berberine (BBR) has gained considerable attention because of its anti-tumor activity. BBR can induce apoptosis of acute lymphoblastic leukemia (ALL) cells through the MDM2/p53 pathway. However, the effects of BBR on those ALL patients with p53 deficiency remain unclear. Results: We found...

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Detalles Bibliográficos
Autores principales: Liu, Jian, Chen, Zhiwei, Cui, Yunping, Wei, Huixia, Zhu, Zhenjing, Mao, Fengxia, Wang, Yingchao, Liu, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066883/
https://www.ncbi.nlm.nih.gov/pubmed/32062612
http://dx.doi.org/10.18632/aging.102813