Incorporation of methotrexate into coconut oil nanoemulsion potentiates its antiproliferation activity and attenuates its oxidative stress

Methotrexate (MTX), a chemotherapeutic agent, has limited clinical applications due to its pulmonary and neurotoxicity. The antineoplastic activity of MTX-NE COCO, which is MTX formulated in coconut oil nanoemulsion (NE), was evaluated in A549 non-small cell lung cancer cells while its adverse side...

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Detalles Bibliográficos
Autores principales: Alkhatib, Mayson H., Alyamani, Shaza A., Abdu, Faiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067161/
https://www.ncbi.nlm.nih.gov/pubmed/32133872
http://dx.doi.org/10.1080/10717544.2020.1736209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067161/
https://www.ncbi.nlm.nih.gov/pubmed/32133872
http://dx.doi.org/10.1080/10717544.2020.1736209

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