Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China

We report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceft...

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Detalles Bibliográficos
Autores principales: Chen, Shao-Chun, Hu, Li-Hua, Zhu, Xiao-Yu, Yin, Yue-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067170/
https://www.ncbi.nlm.nih.gov/pubmed/32116136
http://dx.doi.org/10.1080/22221751.2020.1732836
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author Chen, Shao-Chun
Hu, Li-Hua
Zhu, Xiao-Yu
Yin, Yue-Ping
author_facet Chen, Shao-Chun
Hu, Li-Hua
Zhu, Xiao-Yu
Yin, Yue-Ping
author_sort Chen, Shao-Chun
collection PubMed
description We report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceftriaxone. The SPC high-level resistance (MIC = 2048 mg/L) was due to a small deletion in rspE that caused two amino acid changes in ribosomal protein S5.
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spelling pubmed-70671702020-03-19 Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China Chen, Shao-Chun Hu, Li-Hua Zhu, Xiao-Yu Yin, Yue-Ping Emerg Microbes Infect Letter We report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceftriaxone. The SPC high-level resistance (MIC = 2048 mg/L) was due to a small deletion in rspE that caused two amino acid changes in ribosomal protein S5. Taylor & Francis 2020-03-02 /pmc/articles/PMC7067170/ /pubmed/32116136 http://dx.doi.org/10.1080/22221751.2020.1732836 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter
Chen, Shao-Chun
Hu, Li-Hua
Zhu, Xiao-Yu
Yin, Yue-Ping
Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
title Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
title_full Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
title_fullStr Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
title_full_unstemmed Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
title_short Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China
title_sort gonococcal urethritis caused by a multidrug resistant neisseria gonorrhoeae strain with high-level resistance to spectinomycin in china
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067170/
https://www.ncbi.nlm.nih.gov/pubmed/32116136
http://dx.doi.org/10.1080/22221751.2020.1732836
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