Diminished viability of human ovarian cancer cells by antigen-specific delivery of carbon monoxide with a family of photoactivatable antibody-photoCORM conjugates

Carbon monoxide (CO)-releasing antibody conjugates were synthesized utilizing a photoactivatable CO-releasing molecule (photoCORM) and mouse monoclonal antibodies linked by a biotin-streptavidin system. Different monoclonal antibodies raised against different surface-expressed antigens that are impl...

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Detalles Bibliográficos
Autores principales: Kawahara, Brian, Gao, Lucy, Cohn, Whitaker, Whitelegge, Julian P., Sen, Suvajit, Janzen, Carla, Mascharak, Pradip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067254/
https://www.ncbi.nlm.nih.gov/pubmed/32190266
http://dx.doi.org/10.1039/c9sc03166a

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