Cargando…
Maternal obesity-induced endoplasmic reticulum stress causes metabolic alterations and abnormal hypothalamic development in the offspring
The steady increase in the prevalence of obesity and associated type II diabetes mellitus is a major health concern, particularly among children. Maternal obesity represents a risk factor that contributes to metabolic perturbations in the offspring. Endoplasmic reticulum (ER) stress has emerged as a...
Autores principales: | Park, Soyoung, Jang, Alice, Bouret, Sebastien G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067374/ https://www.ncbi.nlm.nih.gov/pubmed/32163401 http://dx.doi.org/10.1371/journal.pbio.3000296 |
Ejemplares similares
-
SAT-LB104 Maternal Non-Nutritive Sweeteners Consumption Perturbs Development of Melanocortin Circuits Causing Long-Term Metabolic Alterations in the Offspring
por: Park, Soyoung, et al.
Publicado: (2020) -
The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates
por: Park, Soyoung, et al.
Publicado: (2020) -
Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas
por: Soeda, Jumpei, et al.
Publicado: (2016) -
Non-nutritive Sweeteners Induce Hypothalamic ER Stress Causing Abnormal Axon Outgrowth
por: Park, Soyoung, et al.
Publicado: (2019) -
Developmental programming of hypothalamic melanocortin circuits
por: Bouret, Sebastien G.
Publicado: (2022)