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Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy
Speech perception is mediated by both left and right auditory cortices but with differential sensitivity to specific acoustic information contained in the speech signal. A detailed description of this functional asymmetry is missing, and the underlying models are widely debated. We analyzed cortical...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067489/ https://www.ncbi.nlm.nih.gov/pubmed/32119667 http://dx.doi.org/10.1371/journal.pbio.3000207 |
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author | Giroud, Jérémy Trébuchon, Agnès Schön, Daniele Marquis, Patrick Liegeois-Chauvel, Catherine Poeppel, David Morillon, Benjamin |
author_facet | Giroud, Jérémy Trébuchon, Agnès Schön, Daniele Marquis, Patrick Liegeois-Chauvel, Catherine Poeppel, David Morillon, Benjamin |
author_sort | Giroud, Jérémy |
collection | PubMed |
description | Speech perception is mediated by both left and right auditory cortices but with differential sensitivity to specific acoustic information contained in the speech signal. A detailed description of this functional asymmetry is missing, and the underlying models are widely debated. We analyzed cortical responses from 96 epilepsy patients with electrode implantation in left or right primary, secondary, and/or association auditory cortex (AAC). We presented short acoustic transients to noninvasively estimate the dynamical properties of multiple functional regions along the auditory cortical hierarchy. We show remarkably similar bimodal spectral response profiles in left and right primary and secondary regions, with evoked activity composed of dynamics in the theta (around 4–8 Hz) and beta–gamma (around 15–40 Hz) ranges. Beyond these first cortical levels of auditory processing, a hemispheric asymmetry emerged, with delta and beta band (3/15 Hz) responsivity prevailing in the right hemisphere and theta and gamma band (6/40 Hz) activity prevailing in the left. This asymmetry is also present during syllables presentation, but the evoked responses in AAC are more heterogeneous, with the co-occurrence of alpha (around 10 Hz) and gamma (>25 Hz) activity bilaterally. These intracranial data provide a more fine-grained and nuanced characterization of cortical auditory processing in the 2 hemispheres, shedding light on the neural dynamics that potentially shape auditory and speech processing at different levels of the cortical hierarchy. |
format | Online Article Text |
id | pubmed-7067489 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-70674892020-03-23 Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy Giroud, Jérémy Trébuchon, Agnès Schön, Daniele Marquis, Patrick Liegeois-Chauvel, Catherine Poeppel, David Morillon, Benjamin PLoS Biol Research Article Speech perception is mediated by both left and right auditory cortices but with differential sensitivity to specific acoustic information contained in the speech signal. A detailed description of this functional asymmetry is missing, and the underlying models are widely debated. We analyzed cortical responses from 96 epilepsy patients with electrode implantation in left or right primary, secondary, and/or association auditory cortex (AAC). We presented short acoustic transients to noninvasively estimate the dynamical properties of multiple functional regions along the auditory cortical hierarchy. We show remarkably similar bimodal spectral response profiles in left and right primary and secondary regions, with evoked activity composed of dynamics in the theta (around 4–8 Hz) and beta–gamma (around 15–40 Hz) ranges. Beyond these first cortical levels of auditory processing, a hemispheric asymmetry emerged, with delta and beta band (3/15 Hz) responsivity prevailing in the right hemisphere and theta and gamma band (6/40 Hz) activity prevailing in the left. This asymmetry is also present during syllables presentation, but the evoked responses in AAC are more heterogeneous, with the co-occurrence of alpha (around 10 Hz) and gamma (>25 Hz) activity bilaterally. These intracranial data provide a more fine-grained and nuanced characterization of cortical auditory processing in the 2 hemispheres, shedding light on the neural dynamics that potentially shape auditory and speech processing at different levels of the cortical hierarchy. Public Library of Science 2020-03-02 /pmc/articles/PMC7067489/ /pubmed/32119667 http://dx.doi.org/10.1371/journal.pbio.3000207 Text en © 2020 Giroud et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Giroud, Jérémy Trébuchon, Agnès Schön, Daniele Marquis, Patrick Liegeois-Chauvel, Catherine Poeppel, David Morillon, Benjamin Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
title | Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
title_full | Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
title_fullStr | Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
title_full_unstemmed | Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
title_short | Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
title_sort | asymmetric sampling in human auditory cortex reveals spectral processing hierarchy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067489/ https://www.ncbi.nlm.nih.gov/pubmed/32119667 http://dx.doi.org/10.1371/journal.pbio.3000207 |
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