Kounis Syndrome Induced by Protamine Sulfate

Protamine sulfate is considered a “life-saving” antidote for heparinized patients with major bleeds. Although the beneficial attributes and application of protamine sulfate in various clinical settings cannot be argued, it also has an impressive side-effect profile. Kounis syndrome (KS) is an acute...

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Detalles Bibliográficos
Autores principales: Amro, Mohammad, Mansoor, Kanaan, Amro, Ahmed, Okoro, Kelechukwu, Okhumale, Paul I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067578/
https://www.ncbi.nlm.nih.gov/pubmed/32190518
http://dx.doi.org/10.7759/cureus.6972
Descripción
Sumario:Protamine sulfate is considered a “life-saving” antidote for heparinized patients with major bleeds. Although the beneficial attributes and application of protamine sulfate in various clinical settings cannot be argued, it also has an impressive side-effect profile. Kounis syndrome (KS) is an acute coronary syndrome in the setting of an allergic reaction, which can be induced by numerous allergens. Herein, we report a case of KS secondary to the use of protamine sulfate after cryoablation for atrial fibrillation.

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