Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture

A 78-year-old woman presented with an inferior ST-segment elevation myocardial infarction in the setting of a fall resulting in facial trauma causing an unrecognized C6 cervical endplate fracture. After administration of tenecteplase, she developed a spinal epidural hematoma requiring intubation for...

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Detalles Bibliográficos
Autores principales: Parr, Christopher J., Yan, Weiang, Toleva, Olga, Ducas, John, Garber, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067686/
https://www.ncbi.nlm.nih.gov/pubmed/32190828
http://dx.doi.org/10.1016/j.cjco.2019.12.003
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author Parr, Christopher J.
Yan, Weiang
Toleva, Olga
Ducas, John
Garber, Philip J.
author_facet Parr, Christopher J.
Yan, Weiang
Toleva, Olga
Ducas, John
Garber, Philip J.
author_sort Parr, Christopher J.
collection PubMed
description A 78-year-old woman presented with an inferior ST-segment elevation myocardial infarction in the setting of a fall resulting in facial trauma causing an unrecognized C6 cervical endplate fracture. After administration of tenecteplase, she developed a spinal epidural hematoma requiring intubation for airway protection and cessation of antiplatelet therapies. The need to delay coronary intervention in this setting led to a recurrent inferolateral ST-segment elevation myocardial infarction that eventually required coronary bypass grafting. In the first report of a spinal epidural hematoma after tenecteplase for ST-segment elevation myocardial infarction, we emphasize the need for imaging after significant trauma before initiating thrombolysis.
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spelling pubmed-70676862020-03-18 Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture Parr, Christopher J. Yan, Weiang Toleva, Olga Ducas, John Garber, Philip J. CJC Open Case Report A 78-year-old woman presented with an inferior ST-segment elevation myocardial infarction in the setting of a fall resulting in facial trauma causing an unrecognized C6 cervical endplate fracture. After administration of tenecteplase, she developed a spinal epidural hematoma requiring intubation for airway protection and cessation of antiplatelet therapies. The need to delay coronary intervention in this setting led to a recurrent inferolateral ST-segment elevation myocardial infarction that eventually required coronary bypass grafting. In the first report of a spinal epidural hematoma after tenecteplase for ST-segment elevation myocardial infarction, we emphasize the need for imaging after significant trauma before initiating thrombolysis. Elsevier 2019-12-28 /pmc/articles/PMC7067686/ /pubmed/32190828 http://dx.doi.org/10.1016/j.cjco.2019.12.003 Text en © 2019 Canadian Cardiovascular Society. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Parr, Christopher J.
Yan, Weiang
Toleva, Olga
Ducas, John
Garber, Philip J.
Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture
title Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture
title_full Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture
title_fullStr Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture
title_full_unstemmed Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture
title_short Spinal Epidural Hematoma Secondary to Tenecteplase for ST-Elevation Myocardial Infarction in the Setting of Trauma and Cervical Endplate Fracture
title_sort spinal epidural hematoma secondary to tenecteplase for st-elevation myocardial infarction in the setting of trauma and cervical endplate fracture
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067686/
https://www.ncbi.nlm.nih.gov/pubmed/32190828
http://dx.doi.org/10.1016/j.cjco.2019.12.003
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