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Double-Blind Placebo-Controlled Pilot Investigation of the Safety of a Single Dose of Rapid-Acting Intranasal Insulin in Down Syndrome
BACKGROUND: Individuals with Down syndrome are likely to develop clinical and neuropathological brain changes resembling Alzheimer’s disease dementia by the ages of 35–40 years. Intranasal insulin is a potential treatment for neurodegenerative disease that has been shown to reduce amyloid plaque bur...
Autores principales: | Rosenbloom, Michael, Barclay, Terry, Johnsen, Justin, Erickson, Lauren, Svitak, Aleta, Pyle, Maria, Frey, William, Hanson, Leah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067723/ https://www.ncbi.nlm.nih.gov/pubmed/32077057 http://dx.doi.org/10.1007/s40268-020-00296-2 |
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