Immunization of mice with chimeric antigens displaying selected epitopes confers protection against intestinal colonization and renal damage caused by Shiga toxin-producing Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) cause diarrhea and dysentery, which may progress to hemolytic uremic syndrome (HUS). Vaccination has been proposed as a preventive approach against STEC infection; however, there is no vaccine for humans and those used in animals reduce but do not elimin...

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Detalles Bibliográficos
Autores principales: Montero, David A., Del Canto, Felipe, Salazar, Juan C., Céspedes, Sandra, Cádiz, Leandro, Arenas-Salinas, Mauricio, Reyes, José, Oñate, Ángel, Vidal, Roberto M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067774/
https://www.ncbi.nlm.nih.gov/pubmed/32194997
http://dx.doi.org/10.1038/s41541-020-0168-7

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