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Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study

To investigate the association between central obesity and outcomes following in-hospital cardiac arrest (IHCA). A single-centred retrospective study was conducted. Adult patients that experienced IHCA during 2006–2015 were screened. Body mass index (BMI) was calculated at hospital admission. Centra...

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Autores principales: Wang, Chih-Hung, Chang, Wei-Tien, Huang, Chien-Hua, Tsai, Min-Shan, Lu, Tsung-Chien, Chou, Eric, Wu, Yen-Wen, Chen, Wen-Jone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067829/
https://www.ncbi.nlm.nih.gov/pubmed/32165678
http://dx.doi.org/10.1038/s41598-020-61426-z
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author Wang, Chih-Hung
Chang, Wei-Tien
Huang, Chien-Hua
Tsai, Min-Shan
Lu, Tsung-Chien
Chou, Eric
Wu, Yen-Wen
Chen, Wen-Jone
author_facet Wang, Chih-Hung
Chang, Wei-Tien
Huang, Chien-Hua
Tsai, Min-Shan
Lu, Tsung-Chien
Chou, Eric
Wu, Yen-Wen
Chen, Wen-Jone
author_sort Wang, Chih-Hung
collection PubMed
description To investigate the association between central obesity and outcomes following in-hospital cardiac arrest (IHCA). A single-centred retrospective study was conducted. Adult patients that experienced IHCA during 2006–2015 were screened. Body mass index (BMI) was calculated at hospital admission. Central obesity-related anthropometric parameters were measured by analysing computed tomography images. A total of 648 patients were included, with mean BMI of 23.0 kg/m(2). The proportions of BMI-defined obesity in this cohort were underweight (13.1%), normal weight (41.4%), overweight (31.5%) and obesity (14.0%). The mean waist circumference was 85.9 cm with mean waist-to-height ratio (WHtR) of 0.53. The mean sagittal abdominal diameter was 21.2 cm with mean anterior and posterior abdominal subcutaneous adipose tissue (SAT) depths of 1.6 and 2.0 cm, respectively. Multivariate logistic regression analyses indicated BMI of 11.7–23.3 kg/m(2) (odds ratio [OR]: 2.53, 95% confidence interval [CI]: 1.10–5.85; p-value = 0.03), WHtR of 0.49–0.59 (OR: 3.45, 95% CI: 1.56–7.65; p-value = 0.002) and anterior abdominal SAT depth <1.9 cm (OR: 2.84, 95% CI: 1.05–7.74; p-value = 0.04) were positively associated with the favourable neurological outcome. Central obesity was associated with poor IHCA outcomes, after adjusting for the effects of BMI.
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spelling pubmed-70678292020-03-19 Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study Wang, Chih-Hung Chang, Wei-Tien Huang, Chien-Hua Tsai, Min-Shan Lu, Tsung-Chien Chou, Eric Wu, Yen-Wen Chen, Wen-Jone Sci Rep Article To investigate the association between central obesity and outcomes following in-hospital cardiac arrest (IHCA). A single-centred retrospective study was conducted. Adult patients that experienced IHCA during 2006–2015 were screened. Body mass index (BMI) was calculated at hospital admission. Central obesity-related anthropometric parameters were measured by analysing computed tomography images. A total of 648 patients were included, with mean BMI of 23.0 kg/m(2). The proportions of BMI-defined obesity in this cohort were underweight (13.1%), normal weight (41.4%), overweight (31.5%) and obesity (14.0%). The mean waist circumference was 85.9 cm with mean waist-to-height ratio (WHtR) of 0.53. The mean sagittal abdominal diameter was 21.2 cm with mean anterior and posterior abdominal subcutaneous adipose tissue (SAT) depths of 1.6 and 2.0 cm, respectively. Multivariate logistic regression analyses indicated BMI of 11.7–23.3 kg/m(2) (odds ratio [OR]: 2.53, 95% confidence interval [CI]: 1.10–5.85; p-value = 0.03), WHtR of 0.49–0.59 (OR: 3.45, 95% CI: 1.56–7.65; p-value = 0.002) and anterior abdominal SAT depth <1.9 cm (OR: 2.84, 95% CI: 1.05–7.74; p-value = 0.04) were positively associated with the favourable neurological outcome. Central obesity was associated with poor IHCA outcomes, after adjusting for the effects of BMI. Nature Publishing Group UK 2020-03-12 /pmc/articles/PMC7067829/ /pubmed/32165678 http://dx.doi.org/10.1038/s41598-020-61426-z Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wang, Chih-Hung
Chang, Wei-Tien
Huang, Chien-Hua
Tsai, Min-Shan
Lu, Tsung-Chien
Chou, Eric
Wu, Yen-Wen
Chen, Wen-Jone
Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study
title Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study
title_full Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study
title_fullStr Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study
title_full_unstemmed Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study
title_short Associations between Central Obesity and Outcomes of Adult In-hospital Cardiac Arrest: A Retrospective Cohort Study
title_sort associations between central obesity and outcomes of adult in-hospital cardiac arrest: a retrospective cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067829/
https://www.ncbi.nlm.nih.gov/pubmed/32165678
http://dx.doi.org/10.1038/s41598-020-61426-z
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