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Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease linked to oxidative stress, which is associated with significant morbidity. The NADPH oxidase complex (NOX) produces reactive oxygen species (ROS) that are among the key markers for determining RA’s pathophysiology. Therefore, un...

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Detalles Bibliográficos
Autores principales:	Kim, Ye-Ram, Kim, Jae-Sung, Gu, Su-Jin, Jo, Sungsin, Kim, Sojin, Young Kim, Sun, Lee, Daeun, Jang, Kiseok, Choo, Hyunah, Kim, Tae-Hwan, Jung, Jae U., Min, Sun-Joon, Yang, Chul-Su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067850/ https://www.ncbi.nlm.nih.gov/pubmed/32165681 http://dx.doi.org/10.1038/s41598-020-61630-x

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