PD-L1 monoclonal antibody-decorated nanoliposomes loaded with Paclitaxel and P-gp transport inhibitor for the synergistic chemotherapy against multidrug resistant gastric cancers

Multidrug resistance (MDR) based on ATP-dependent efflux transporters (p-glycoprotein (p-gp)) remains a major obstacle in successful chemotherapy treatment. Herein, we have investigated the potential of PD-L1 mAb-conjugated nanoliposome to serve as a targeted delivery platform for the co-delivery of...

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Detalles Bibliográficos
Autores principales: Yu, Jinling, Hu, Fengli, Zhu, Qiankun, Li, Xiaodong, Ren, Haiyang, Fan, Shengjie, Qian, Bo, Zhai, Bo, Yang, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067943/
https://www.ncbi.nlm.nih.gov/pubmed/32166458
http://dx.doi.org/10.1186/s11671-019-3228-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067943/
https://www.ncbi.nlm.nih.gov/pubmed/32166458
http://dx.doi.org/10.1186/s11671-019-3228-z

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