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Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells

Human pluripotent stem cells (hPSCs) and mesenchymal stromal/stem cells (hMSCs) are clinically relevant sources for cellular therapies and for modeling human development and disease. Many stem cell-based applications rely on the ability to activate several endogenous genes simultaneously to modify c...

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Detalles Bibliográficos
Autores principales: Petazzi, Paolo, Torres-Ruiz, Raul, Fidanza, Antonella, Roca-Ho, Heleia, Gutierrez-Agüera, Francisco, Castaño, Julio, Rodriguez-Perales, Sandra, Díaz de la Guardia, Rafael, López-Millán, Belén, Bigas, Anna, Forrester, Lesley M., Bueno, Clara, Menéndez, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068053/
https://www.ncbi.nlm.nih.gov/pubmed/32171171
http://dx.doi.org/10.1016/j.omtn.2020.02.009