NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer

Oncolytic viruses (OVs) can trigger profound innate and adaptive immune responses, which have the potential both to potentiate and reduce the activity of OVs. Natural killer (NK) cells can mediate potent anti-viral and anti-tumoral responses, but there are no data on the role of NK cells in oncolyti...

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Detalles Bibliográficos
Autores principales: Leung, Elaine Y.L., Ennis, Darren P., Kennedy, Philippa R., Hansell, Christopher, Dowson, Suzanne, Farquharson, Malcolm, Spiliopoulou, Pavlina, Nautiyal, Jaya, McNamara, Sophie, Carlin, Leo M., Fisher, Kerry, Davis, Daniel M., Graham, Gerard, McNeish, Iain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068056/
https://www.ncbi.nlm.nih.gov/pubmed/32195317
http://dx.doi.org/10.1016/j.omto.2020.02.001

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