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Radiation therapy for oligometastatic oropharyngeal cancer
At presentation, isolated metastasis from oropharyngeal squamous cell carcinoma is rare. Liver is a relatively uncommon first site of failure, especially in the absence of other distant metastases, particularly without diagnosis of lung metastases. We report on a case of HPV-related oropharyngeal sq...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068095/ https://www.ncbi.nlm.nih.gov/pubmed/32201599 http://dx.doi.org/10.1259/bjrcr.20190021 |
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author | Martini, Stefania Arcadipane, Francesca Franco, Pierfrancesco Iorio, Giuseppe C. Bartoncini, Sara Gallio, Elena Guarneri, Alessia S. Ricardi, Umberto |
author_facet | Martini, Stefania Arcadipane, Francesca Franco, Pierfrancesco Iorio, Giuseppe C. Bartoncini, Sara Gallio, Elena Guarneri, Alessia S. Ricardi, Umberto |
author_sort | Martini, Stefania |
collection | PubMed |
description | At presentation, isolated metastasis from oropharyngeal squamous cell carcinoma is rare. Liver is a relatively uncommon first site of failure, especially in the absence of other distant metastases, particularly without diagnosis of lung metastases. We report on a case of HPV-related oropharyngeal squamous cell carcinoma with synchronous liver metastasis treated with radiation therapy. This condition, defined as "oligometastatic state," describes a subset of patients with limited volume metastatic disease in whom favorable outcomes were reported with the use of local ablative therapies on both the primary tumor and metastatic sites. As a definitive treatment, we offered the patient, ineligible for other therapeutic approaches, exclusive radiation treatment on the head and neck region and a stereotactic ablative approach targeted to the liver metastasis. |
format | Online Article Text |
id | pubmed-7068095 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70680952020-03-20 Radiation therapy for oligometastatic oropharyngeal cancer Martini, Stefania Arcadipane, Francesca Franco, Pierfrancesco Iorio, Giuseppe C. Bartoncini, Sara Gallio, Elena Guarneri, Alessia S. Ricardi, Umberto BJR Case Rep Case Report At presentation, isolated metastasis from oropharyngeal squamous cell carcinoma is rare. Liver is a relatively uncommon first site of failure, especially in the absence of other distant metastases, particularly without diagnosis of lung metastases. We report on a case of HPV-related oropharyngeal squamous cell carcinoma with synchronous liver metastasis treated with radiation therapy. This condition, defined as "oligometastatic state," describes a subset of patients with limited volume metastatic disease in whom favorable outcomes were reported with the use of local ablative therapies on both the primary tumor and metastatic sites. As a definitive treatment, we offered the patient, ineligible for other therapeutic approaches, exclusive radiation treatment on the head and neck region and a stereotactic ablative approach targeted to the liver metastasis. The British Institute of Radiology. 2020-02-12 /pmc/articles/PMC7068095/ /pubmed/32201599 http://dx.doi.org/10.1259/bjrcr.20190021 Text en © 2020 The Authors. Published by the British Institute of Radiology This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Case Report Martini, Stefania Arcadipane, Francesca Franco, Pierfrancesco Iorio, Giuseppe C. Bartoncini, Sara Gallio, Elena Guarneri, Alessia S. Ricardi, Umberto Radiation therapy for oligometastatic oropharyngeal cancer |
title | Radiation therapy for oligometastatic oropharyngeal cancer |
title_full | Radiation therapy for oligometastatic oropharyngeal cancer |
title_fullStr | Radiation therapy for oligometastatic oropharyngeal cancer |
title_full_unstemmed | Radiation therapy for oligometastatic oropharyngeal cancer |
title_short | Radiation therapy for oligometastatic oropharyngeal cancer |
title_sort | radiation therapy for oligometastatic oropharyngeal cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068095/ https://www.ncbi.nlm.nih.gov/pubmed/32201599 http://dx.doi.org/10.1259/bjrcr.20190021 |
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