Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review

Magnetic resonance spectroscopy (MRS) is a promising non-invasive diagnostic method that can detect and quantify endogenous tissue metabolites. High glycine levels obtained from ex vivo breast MRS have been associated with poor prognosis; however, glycine evaluation has not been reported regarding i...

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Detalles Bibliográficos
Autores principales: Bitencourt, Almir G.V., Pinker, Katja, Thakur, Sunitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068099/
https://www.ncbi.nlm.nih.gov/pubmed/32201616
http://dx.doi.org/10.1259/bjrcr.20190090
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author Bitencourt, Almir G.V.
Pinker, Katja
Thakur, Sunitha
author_facet Bitencourt, Almir G.V.
Pinker, Katja
Thakur, Sunitha
author_sort Bitencourt, Almir G.V.
collection PubMed
description Magnetic resonance spectroscopy (MRS) is a promising non-invasive diagnostic method that can detect and quantify endogenous tissue metabolites. High glycine levels obtained from ex vivo breast MRS have been associated with poor prognosis; however, glycine evaluation has not been reported regarding in vivo MRS. We report our finding in a breast cancer patient in whom pre-treatment but not post-treatment in vivo MRS showed elevated glycine and discuss the implications of this finding.
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spelling pubmed-70680992020-03-20 Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review Bitencourt, Almir G.V. Pinker, Katja Thakur, Sunitha BJR Case Rep Case Report Magnetic resonance spectroscopy (MRS) is a promising non-invasive diagnostic method that can detect and quantify endogenous tissue metabolites. High glycine levels obtained from ex vivo breast MRS have been associated with poor prognosis; however, glycine evaluation has not been reported regarding in vivo MRS. We report our finding in a breast cancer patient in whom pre-treatment but not post-treatment in vivo MRS showed elevated glycine and discuss the implications of this finding. The British Institute of Radiology. 2020-02-12 /pmc/articles/PMC7068099/ /pubmed/32201616 http://dx.doi.org/10.1259/bjrcr.20190090 Text en © 2020 The Authors. Published by the British Institute of Radiology This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Bitencourt, Almir G.V.
Pinker, Katja
Thakur, Sunitha
Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
title Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
title_full Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
title_fullStr Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
title_full_unstemmed Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
title_short Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
title_sort elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068099/
https://www.ncbi.nlm.nih.gov/pubmed/32201616
http://dx.doi.org/10.1259/bjrcr.20190090
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AT thakursunitha elevatedglycinedetectedoninvivomagneticresonancespectroscopyinabreastcancerpatientcasereportandliteraturereview

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