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Maspin inhibits MCF-7 cell invasion and proliferation by downregulating miR-21 and increasing the expression of its target genes

Maspin has been identified as a tumor suppressor gene in breast cancer, but the underlying regulatory mechanisms remain unclear. In the present study, maspin pcDNA was transfected into MCF-7 cells. microRNA (miR) microarray and reverse transcription-quantitative polymerase chain reaction was used fo...

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Detalles Bibliográficos
Autores principales:	Huang, Shao-Xin, Fan, Wen-Yan, Wang, Ling, Liu, Hui, Wang, Xin, Zhao, Hao, Jiang, Wen-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068223/ https://www.ncbi.nlm.nih.gov/pubmed/32218812 http://dx.doi.org/10.3892/ol.2020.11360

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