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Relationships Between Immune Landscapes, Genetic Subtypes and Responses to Immunotherapy in Colorectal Cancer

Colorectal cancer (CRC) is highly heterogeneous at the genetic and molecular level, which has major repercussions on the efficacy of immunotherapy. A small subset of CRCs exhibit microsatellite instability (MSI), a molecular indicator of defective DNA mismatch repair (MMR), but the majority are micr...

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Detalles Bibliográficos
Autores principales:	Picard, Emilie, Verschoor, Chris P., Ma, Grace W., Pawelec, Graham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068608/ https://www.ncbi.nlm.nih.gov/pubmed/32210966 http://dx.doi.org/10.3389/fimmu.2020.00369

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