Cargando…
Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
BACKGROUND: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized. OBJECTIVES: To provide a better understanding of th...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068618/ https://www.ncbi.nlm.nih.gov/pubmed/32190761 http://dx.doi.org/10.1016/j.heliyon.2020.e03547 |
_version_ | 1783505621348253696 |
---|---|
author | Clanner-Engelshofen, Benjamin M. Marsela, Enklajd Engelsberger, Nicole Guertler, Anne Schauber, Jürgen French, Lars E. Reinholz, Markus |
author_facet | Clanner-Engelshofen, Benjamin M. Marsela, Enklajd Engelsberger, Nicole Guertler, Anne Schauber, Jürgen French, Lars E. Reinholz, Markus |
author_sort | Clanner-Engelshofen, Benjamin M. |
collection | PubMed |
description | BACKGROUND: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized. OBJECTIVES: To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease. METHODS: Data of 1124 patients with a confirmed diagnosis of CA, presenting in our university hospital outpatient consultation between 2011 and 2015 were retrospectively evaluated and the efficacy of various types of treatments was addressed. RESULTS: A large patient cohort of 1124 predominately young (mean age 36.5 years old), male (83.9 %), single (50.2 %), heterosexual (92.8 %) Germans (62.5 %) received consults in our outpatient clinic for STDs. Nearly 60 % of the diagnosed patients presented with first-time CA, indicating a considerable proportion of roughly 40 % recurrent infections as well. Only 13.7 % of patients were previously immunized against HPV. CONCLUSIONS: The evaluation of a large patient cohort provided a better understanding of the present epidemiology of CA in an outpatient hospital setting in Germany. An effective three-scale therapeutic regime and preventive measures were outlined. |
format | Online Article Text |
id | pubmed-7068618 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70686182020-03-18 Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options Clanner-Engelshofen, Benjamin M. Marsela, Enklajd Engelsberger, Nicole Guertler, Anne Schauber, Jürgen French, Lars E. Reinholz, Markus Heliyon Article BACKGROUND: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized. OBJECTIVES: To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease. METHODS: Data of 1124 patients with a confirmed diagnosis of CA, presenting in our university hospital outpatient consultation between 2011 and 2015 were retrospectively evaluated and the efficacy of various types of treatments was addressed. RESULTS: A large patient cohort of 1124 predominately young (mean age 36.5 years old), male (83.9 %), single (50.2 %), heterosexual (92.8 %) Germans (62.5 %) received consults in our outpatient clinic for STDs. Nearly 60 % of the diagnosed patients presented with first-time CA, indicating a considerable proportion of roughly 40 % recurrent infections as well. Only 13.7 % of patients were previously immunized against HPV. CONCLUSIONS: The evaluation of a large patient cohort provided a better understanding of the present epidemiology of CA in an outpatient hospital setting in Germany. An effective three-scale therapeutic regime and preventive measures were outlined. Elsevier 2020-03-11 /pmc/articles/PMC7068618/ /pubmed/32190761 http://dx.doi.org/10.1016/j.heliyon.2020.e03547 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Clanner-Engelshofen, Benjamin M. Marsela, Enklajd Engelsberger, Nicole Guertler, Anne Schauber, Jürgen French, Lars E. Reinholz, Markus Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options |
title | Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options |
title_full | Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options |
title_fullStr | Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options |
title_full_unstemmed | Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options |
title_short | Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options |
title_sort | condylomata acuminata: a retrospective analysis on clinical characteristics and treatment options |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068618/ https://www.ncbi.nlm.nih.gov/pubmed/32190761 http://dx.doi.org/10.1016/j.heliyon.2020.e03547 |
work_keys_str_mv | AT clannerengelshofenbenjaminm condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions AT marselaenklajd condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions AT engelsbergernicole condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions AT guertleranne condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions AT schauberjurgen condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions AT frenchlarse condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions AT reinholzmarkus condylomataacuminataaretrospectiveanalysisonclinicalcharacteristicsandtreatmentoptions |