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Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options

BACKGROUND: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized. OBJECTIVES: To provide a better understanding of th...

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Autores principales: Clanner-Engelshofen, Benjamin M., Marsela, Enklajd, Engelsberger, Nicole, Guertler, Anne, Schauber, Jürgen, French, Lars E., Reinholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068618/
https://www.ncbi.nlm.nih.gov/pubmed/32190761
http://dx.doi.org/10.1016/j.heliyon.2020.e03547
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author Clanner-Engelshofen, Benjamin M.
Marsela, Enklajd
Engelsberger, Nicole
Guertler, Anne
Schauber, Jürgen
French, Lars E.
Reinholz, Markus
author_facet Clanner-Engelshofen, Benjamin M.
Marsela, Enklajd
Engelsberger, Nicole
Guertler, Anne
Schauber, Jürgen
French, Lars E.
Reinholz, Markus
author_sort Clanner-Engelshofen, Benjamin M.
collection PubMed
description BACKGROUND: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized. OBJECTIVES: To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease. METHODS: Data of 1124 patients with a confirmed diagnosis of CA, presenting in our university hospital outpatient consultation between 2011 and 2015 were retrospectively evaluated and the efficacy of various types of treatments was addressed. RESULTS: A large patient cohort of 1124 predominately young (mean age 36.5 years old), male (83.9 %), single (50.2 %), heterosexual (92.8 %) Germans (62.5 %) received consults in our outpatient clinic for STDs. Nearly 60 % of the diagnosed patients presented with first-time CA, indicating a considerable proportion of roughly 40 % recurrent infections as well. Only 13.7 % of patients were previously immunized against HPV. CONCLUSIONS: The evaluation of a large patient cohort provided a better understanding of the present epidemiology of CA in an outpatient hospital setting in Germany. An effective three-scale therapeutic regime and preventive measures were outlined.
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spelling pubmed-70686182020-03-18 Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options Clanner-Engelshofen, Benjamin M. Marsela, Enklajd Engelsberger, Nicole Guertler, Anne Schauber, Jürgen French, Lars E. Reinholz, Markus Heliyon Article BACKGROUND: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized. OBJECTIVES: To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease. METHODS: Data of 1124 patients with a confirmed diagnosis of CA, presenting in our university hospital outpatient consultation between 2011 and 2015 were retrospectively evaluated and the efficacy of various types of treatments was addressed. RESULTS: A large patient cohort of 1124 predominately young (mean age 36.5 years old), male (83.9 %), single (50.2 %), heterosexual (92.8 %) Germans (62.5 %) received consults in our outpatient clinic for STDs. Nearly 60 % of the diagnosed patients presented with first-time CA, indicating a considerable proportion of roughly 40 % recurrent infections as well. Only 13.7 % of patients were previously immunized against HPV. CONCLUSIONS: The evaluation of a large patient cohort provided a better understanding of the present epidemiology of CA in an outpatient hospital setting in Germany. An effective three-scale therapeutic regime and preventive measures were outlined. Elsevier 2020-03-11 /pmc/articles/PMC7068618/ /pubmed/32190761 http://dx.doi.org/10.1016/j.heliyon.2020.e03547 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Clanner-Engelshofen, Benjamin M.
Marsela, Enklajd
Engelsberger, Nicole
Guertler, Anne
Schauber, Jürgen
French, Lars E.
Reinholz, Markus
Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
title Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
title_full Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
title_fullStr Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
title_full_unstemmed Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
title_short Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options
title_sort condylomata acuminata: a retrospective analysis on clinical characteristics and treatment options
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068618/
https://www.ncbi.nlm.nih.gov/pubmed/32190761
http://dx.doi.org/10.1016/j.heliyon.2020.e03547
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