Cargando…

Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms

Carteolol is a non-selective β-adrenoceptor antagonist used for the treatment of glaucoma, and its abuse might be cytotoxic to the cornea. However, its cytotoxicity and underlying mechanisms need to be elucidated. Herein, we used an in vivo model of feline corneas and an in vitro model of human corn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Wen, Zhao, Jun, Fan, Ting-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068677/ https://www.ncbi.nlm.nih.gov/pubmed/32210806 http://dx.doi.org/10.3389/fphar.2020.00202

Ejemplares similares

Enhancement in Corneal Permeability of Dissolved Carteolol by Its Combination with Magnesium Hydroxide Nanoparticles
por: Nagai, Noriaki, et al.
Publicado: (2018)

Efficacy and safety of the fixed combinations of tafluprost/timolol and latanoprost/carteolol
por: Fuwa, Masahiro, et al.
Publicado: (2019)

Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost
por: Nutterova, Elena, et al.
Publicado: (2022)

Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
por: Eto, Ryo, et al.
Publicado: (2022)

Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics
por: Copaescu, Ana, et al.
Publicado: (2021)

Corrigendum: Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics
por: Copaescu, Ana, et al.
Publicado: (2021)

Diabetic Corneal Neuropathy: Pathogenic Mechanisms and Therapeutic Strategies
por: Zhou, Ting, et al.
Publicado: (2022)

Dose- and time-dependent manners of moxifloxacin induced liver injury by targeted metabolomics study
por: Hu, Ting, et al.
Publicado: (2022)

Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction
por: Yeo, Natalie Jia Ying, et al.
Publicado: (2019)

Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta
por: Zhou, Zhong-Yan, et al.
Publicado: (2019)

A comparative study between a transscleral sustained-release device and eyedrops on intraocular distribution of carteolol hydrochloride
por: Hashikawa, Yoshiko, et al.
Publicado: (2023)

Analgesic Effects of Duloxetine on Formalin-Induced Hyperalgesia and Its Underlying Mechanisms in the CeA
por: Zhang, Lie, et al.
Publicado: (2018)

Potential role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy
por: Dubchak, Eden, et al.
Publicado: (2022)

Short-Term Efficacy and Safety of Switching from a Latanoprost/Timolol Fixed Combination to a Latanoprost/Carteolol Fixed Combination
por: Inoue, Kenji, et al.
Publicado: (2020)

Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
por: Arai, Riku, et al.
Publicado: (2020)

Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases
por: Wu, Duoduo, et al.
Publicado: (2021)

Application of a Physiologically Based Pharmacokinetic Model to Characterize Time-dependent Metabolism of Voriconazole in Children and Support Dose Optimization
por: Zhang, Yahui, et al.
Publicado: (2021)

A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells
por: Bai, Jing, et al.
Publicado: (2020)

Carteolol Hydrochloride Suppresses the Generation of Reactive Oxygen Species and Rescues Cell Death After Ultraviolet Irradiation of Cultured Lens Epithelial Cells
por: Kaji, Yuichi, et al.
Publicado: (2010)

Specific Interaction With Human Serum Albumin Reduces Ginsenoside Cytotoxicity in Human Umbilical Vein Endothelial Cells
por: Li, He, et al.
Publicado: (2020)

Evaluation of cytotoxicity of bevacizumab on VEGF-enriched corneal endothelial cells
por: Rusovici, Raluca, et al.
Publicado: (2011)

Evaluation of moxifloxacin-induced cytotoxicity on human corneal endothelial cells
por: Park, Joo-Hee, et al.
Publicado: (2021)

A Randomized Double-Blinded Dose-dependent Study of Metaraminol for Preventing Spinal-Induced Hypotension in Caesarean Delivery
por: Xiao, Fei, et al.
Publicado: (2021)

p53 status modifies cytotoxic activity of lactoferrin under hypoxic conditions
por: Kosim, Maryami Yuliana, et al.
Publicado: (2022)

Time and Concentration Dependent Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Induced Endothelial Activation
por: Li, Meng, et al.
Publicado: (2018)

Dose- and time-dependent renoprotection of Angelica sinensis in patients with chronic kidney disease: A longitudinal cohort study
por: Chen, Hsiao-Tien, et al.
Publicado: (2023)

The Anticancer Effects of Atractylenolide III Associate With the Downregulation of Jak3/Stat3-Dependent IDO Expression
por: Liu, Jun-bao, et al.
Publicado: (2020)

Mechanisms Underlying Curcumin-Induced Neuroprotection in Cerebral Ischemia
por: Fan, Feng, et al.
Publicado: (2022)

Preparation of a Sunitinib loaded microemulsion for ocular delivery and evaluation for the treatment of corneal neovascularization in vitro and in vivo
por: Shi, Jieran, et al.
Publicado: (2023)

Dose and time-dependent sub-chronic toxicity study of hydroethanolic leaf extract of Flabellaria paniculata Cav. (Malpighiaceae) in rodents
por: Akindele, Abidemi J., et al.
Publicado: (2014)

Dose- and Time-Dependent Cytotoxicity of Layered Black Phosphorus in Fibroblastic Cells
por: Song, Su-Jin, et al.
Publicado: (2018)

Ascorbic Acid Sensitizes Colorectal Carcinoma to the Cytotoxicity of Arsenic Trioxide via Promoting Reactive Oxygen Species-Dependent Apoptosis and Pyroptosis
por: Tian, Wei, et al.
Publicado: (2020)

Low-Dose Piperlongumine Rescues Impaired Function of Endothelial Progenitor Cells and Reduces Cerebral Ischemic Injury in High-Fat Diet-Fed Mice
por: Dong, Xiao-Hui, et al.
Publicado: (2021)

Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
por: Chen, Mengji, et al.
Publicado: (2020)

Effects and Mechanism of Salvianolic Acid B on the Injury of Human Renal Tubular Epithelial Cells Induced by Iopromide
por: Dong, Shu-Jun, et al.
Publicado: (2021)

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats
por: Zhao, Hui, et al.
Publicado: (2019)

Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions
por: Miyazaki, Yukiko, et al.
Publicado: (2018)

The Deletion of Endothelial Sodium Channel α (αENaC) Impairs Endothelium-Dependent Vasodilation and Endothelial Barrier Integrity in Endotoxemia in Vivo
por: Sternak, Magdalena, et al.
Publicado: (2018)

Analysis of Time Course and Dose Effect From Metformin on Body Mass Index in Children and Adolescents
por: Wang, Dong-Dong, et al.
Publicado: (2021)

Polarized Expression of Ion Channels and Solute Carrier Family Transporters on Heterogeneous Cultured Human Corneal Endothelial Cells
por: Hamuro, Junji, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cljv6pr546ntt3ik1dfecutnql