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uORFlight: a vehicle toward uORF-mediated translational regulation mechanisms in eukaryotes
Upstream open reading frames (uORFs) are prevalent in eukaryotic mRNAs. They act as a translational control element for precisely tuning the expression of the downstream major open reading frame (mORF). uORF variation has been clearly associated with several human diseases. In contrast, natural uORF...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068905/ https://www.ncbi.nlm.nih.gov/pubmed/32168374 http://dx.doi.org/10.1093/database/baaa007 |