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Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women

BACKGROUND: The current study’s purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged...

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Autores principales: Saddik, Hayman, Nasr, Riad, Pinti, Antonio, Watelain, Eric, Fayad, Ibrahim, Baddoura, Rafic, Berro, Abdel-Jalil, Al Rassy, Nathalie, Lespessailles, Eric, Toumi, Hechmi, El Hage, Rawad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068911/
https://www.ncbi.nlm.nih.gov/pubmed/32164524
http://dx.doi.org/10.1186/s12859-020-3353-9
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author Saddik, Hayman
Nasr, Riad
Pinti, Antonio
Watelain, Eric
Fayad, Ibrahim
Baddoura, Rafic
Berro, Abdel-Jalil
Al Rassy, Nathalie
Lespessailles, Eric
Toumi, Hechmi
El Hage, Rawad
author_facet Saddik, Hayman
Nasr, Riad
Pinti, Antonio
Watelain, Eric
Fayad, Ibrahim
Baddoura, Rafic
Berro, Abdel-Jalil
Al Rassy, Nathalie
Lespessailles, Eric
Toumi, Hechmi
El Hage, Rawad
author_sort Saddik, Hayman
collection PubMed
description BACKGROUND: The current study’s purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged between 65 and 84 years) with sarcopenia and 60 age-matched controls (with normal skeletal muscle mass index (SMI)). Body composition and bone parameters were evaluated by dual-energy X-ray absorptiometry (DXA). RESULTS: Weight, lean mass, body mass index, femoral neck cross-sectional area (FN CSA), FN section modulus (Z), FN cross sectional moment of inertia (CSMI), intertrochanteric (IT) CSA, IT Z, IT CSMI, IT cortical thickness (CT), femoral shaft (FS) CSA, FS Z and FS CSMI were significantly greater (p < 0.05) in women with normal SMI compared to women with sarcopenia. In the whole population, SMI was positively associated with IT CSA, IT Z, IT CSMI, IT CT, FS CSA, FS Z, FS CSMI, FS CT but negatively correlated to IT buckling ratio (BR) and FS BR. CONCLUSION: The current study suggests that sarcopenia has a negative effect on hip bone strength indices in postmenopausal women.
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spelling pubmed-70689112020-03-18 Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women Saddik, Hayman Nasr, Riad Pinti, Antonio Watelain, Eric Fayad, Ibrahim Baddoura, Rafic Berro, Abdel-Jalil Al Rassy, Nathalie Lespessailles, Eric Toumi, Hechmi El Hage, Rawad BMC Bioinformatics Research BACKGROUND: The current study’s purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged between 65 and 84 years) with sarcopenia and 60 age-matched controls (with normal skeletal muscle mass index (SMI)). Body composition and bone parameters were evaluated by dual-energy X-ray absorptiometry (DXA). RESULTS: Weight, lean mass, body mass index, femoral neck cross-sectional area (FN CSA), FN section modulus (Z), FN cross sectional moment of inertia (CSMI), intertrochanteric (IT) CSA, IT Z, IT CSMI, IT cortical thickness (CT), femoral shaft (FS) CSA, FS Z and FS CSMI were significantly greater (p < 0.05) in women with normal SMI compared to women with sarcopenia. In the whole population, SMI was positively associated with IT CSA, IT Z, IT CSMI, IT CT, FS CSA, FS Z, FS CSMI, FS CT but negatively correlated to IT buckling ratio (BR) and FS BR. CONCLUSION: The current study suggests that sarcopenia has a negative effect on hip bone strength indices in postmenopausal women. BioMed Central 2020-03-11 /pmc/articles/PMC7068911/ /pubmed/32164524 http://dx.doi.org/10.1186/s12859-020-3353-9 Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Saddik, Hayman
Nasr, Riad
Pinti, Antonio
Watelain, Eric
Fayad, Ibrahim
Baddoura, Rafic
Berro, Abdel-Jalil
Al Rassy, Nathalie
Lespessailles, Eric
Toumi, Hechmi
El Hage, Rawad
Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
title Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
title_full Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
title_fullStr Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
title_full_unstemmed Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
title_short Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
title_sort sarcopenia negatively affects hip structure analysis variables in a group of lebanese postmenopausal women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068911/
https://www.ncbi.nlm.nih.gov/pubmed/32164524
http://dx.doi.org/10.1186/s12859-020-3353-9
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