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Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencing

BACKGROUND: Acute lymphoblastic leukemia (ALL), the most common childhood malignancy, is characterized by recurring structural chromosomal alterations and genetic alterations, whose detection is critical in diagnosis, risk stratification and prognostication. However, the genetic mechanisms that give...

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Detalles Bibliográficos
Autores principales: Zhang, Honghong, Wang, Hongsheng, Qian, Xiaowen, Gao, Shuai, Xia, Jieqi, Liu, Junwen, Cheng, Yanqin, Man, Jie, Zhai, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068927/
https://www.ncbi.nlm.nih.gov/pubmed/32164600
http://dx.doi.org/10.1186/s12885-020-6709-7