Cargando…

Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer’s disease

The discovery of mutations associated with familial forms of Alzheimer’s disease (AD), has brought imperative insights into basic mechanisms of disease pathogenesis and progression and has allowed researchers to create animal models that assist in the elucidation of the molecular pathways and develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lloyd, Grace M., Trejo-Lopez, Jorge A., Xia, Yuxing, McFarland, Karen N., Lincoln, Sarah J., Ertekin-Taner, Nilüfer, Giasson, Benoit I., Yachnis, Anthony T., Prokop, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068954/
https://www.ncbi.nlm.nih.gov/pubmed/32164763
http://dx.doi.org/10.1186/s40478-020-0891-3