Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells

BACKGROUND: Metastasis causes the most breast cancer-related deaths in women. Here, we investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the treatment of metastatic breast tumors using 4T1-bearing BALB/c mice. RESULTS: Solid lipid nanoparticles (SLNs) were produce...

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Detalles Bibliográficos
Autores principales: da Rocha, Márcia Cristina Oliveira, da Silva, Patrícia Bento, Radicchi, Marina Arantes, Andrade, Bárbara Yasmin Garcia, de Oliveira, Jaqueline Vaz, Venus, Tom, Merker, Carolin, Estrela-Lopis, Irina, Longo, João Paulo Figueiró, Báo, Sônia Nair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068958/
https://www.ncbi.nlm.nih.gov/pubmed/32164731
http://dx.doi.org/10.1186/s12951-020-00604-7

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