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Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy
BACKGROUND: Rapamycin is known to be effective in suppressing senescence and the senescence-associated secretory phenotype (SASP). Therefore, it is highly expected to represent an anti-aging drug. Its anti-aging effect has been demonstrated at the mouse individual level. However, there are not many...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069020/ https://www.ncbi.nlm.nih.gov/pubmed/32164764 http://dx.doi.org/10.1186/s12964-020-00533-w |