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Network hub-node prioritization of gene regulation with intra-network association

BACKGROUND: To identify and prioritize the influential hub genes in a gene-set or biological pathway, most analyses rely on calculation of marginal effects or tests of statistical significance. These procedures may be inappropriate since hub nodes are common connection points and therefore may inter...

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Detalles Bibliográficos
Autores principales:	Chang, Hung-Ching, Chu, Chiao-Pei, Lin, Shu-Ju, Hsiao, Chuhsing Kate
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069025/ https://www.ncbi.nlm.nih.gov/pubmed/32164570 http://dx.doi.org/10.1186/s12859-020-3444-7

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