Cargando…
NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease
Background: Inflammation and steatosis are the main pathological features of alcoholic liver disease (ALD), in which, inflammation is one of the critical drivers for the initiation and development of alcoholic steatosis. NIK, an inflammatory pathway component activated by inflammatory cytokines, was...
Autores principales: | Li, Yaru, Chen, Mingming, Zhou, Yu, Tang, Chuanfeng, Zhang, Wen, Zhong, Ying, Chen, Yadong, Zhou, Hong, Sheng, Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069072/ https://www.ncbi.nlm.nih.gov/pubmed/32206109 http://dx.doi.org/10.7150/thno.40149 |
Ejemplares similares
-
Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway
por: Xu, Lin, et al.
Publicado: (2021) -
Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis
por: Yu, Jung Hwan, et al.
Publicado: (2016) -
PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice
por: Garbacz, Wojciech G., et al.
Publicado: (2015) -
CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis
por: Ju, Linling, et al.
Publicado: (2020) -
Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging
por: Kim, Seong Min, et al.
Publicado: (2017)