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Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy

Rationale: Androgen receptor splice variant 7 (AR-V7) is a leading cause of the development of castration-resistant prostate cancer (CRPC). However, the regulation and function of AR-V7 at levels of post-translational modifications in prostate cancer therapy remain poorly understood. Here, we conduc...

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Detalles Bibliográficos
Autores principales:	Liao, Yuning, Liu, Yuan, Xia, Xiaohong, Shao, Zhenlong, Huang, Chuyi, He, Jinchan, Jiang, Lili, Tang, Daolin, Liu, Jinbao, Huang, Hongbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069092/ https://www.ncbi.nlm.nih.gov/pubmed/32206096 http://dx.doi.org/10.7150/thno.41849

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