A cell-permeable peptide-based PROTAC against the oncoprotein CREPT proficiently inhibits pancreatic cancer

Cancers remain a threat to human health due to the lack of effective therapeutic strategies. Great effort has been devoted to the discovery of drug targets to treat cancers, but novel oncoproteins still need to be unveiled for efficient therapy. Methods: We show that CREPT is highly expressed in pan...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Danhui, Zou, Yutian, Chu, Yunxiang, Liu, Zhengsheng, Liu, Gaochao, Chu, Jun, Li, Mengdi, Wang, Jiayu, Sun, Shi-yong, Chang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069095/
https://www.ncbi.nlm.nih.gov/pubmed/32206117
http://dx.doi.org/10.7150/thno.41677

Ejemplares similares

Ejemplares similares