Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity

Chronic sclerosing sialadenitis is associated with the immunoglobulin G4 (IgG4)-related disease (RD) spectrum. IgG4-RD is a newly recognized immunomediated fibroinflammatory condition characterized by several features: a tendency to form tumefactive lesions at multiple sites, lymphoplasmacytic infil...

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Autores principales: Gurwale, Sushama Govindrao, Gore, Charusheela Rajesh, Gulati, Ishita, Dey, Indranil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069128/
https://www.ncbi.nlm.nih.gov/pubmed/32189922
http://dx.doi.org/10.4103/jomfp.JOMFP_83_17
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author Gurwale, Sushama Govindrao
Gore, Charusheela Rajesh
Gulati, Ishita
Dey, Indranil
author_facet Gurwale, Sushama Govindrao
Gore, Charusheela Rajesh
Gulati, Ishita
Dey, Indranil
author_sort Gurwale, Sushama Govindrao
collection PubMed
description Chronic sclerosing sialadenitis is associated with the immunoglobulin G4 (IgG4)-related disease (RD) spectrum. IgG4-RD is a newly recognized immunomediated fibroinflammatory condition characterized by several features: a tendency to form tumefactive lesions at multiple sites, lymphoplasmacytic infiltrate, fibrosis and obliterative phlebitis. Often but not always, the serum IgG4 concentrations are also elevated. Immunohistochemistry for IgG4 is helpful to clinch the diagnosis. Here, we describe a case of 65-year-old male with IgG4-related chronic sclerosing sialadenitis of the s ubmandibular gland. We have discussed the histopathological criteria to diagnose this entity.
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spelling pubmed-70691282020-03-18 Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity Gurwale, Sushama Govindrao Gore, Charusheela Rajesh Gulati, Ishita Dey, Indranil J Oral Maxillofac Pathol Case Report Chronic sclerosing sialadenitis is associated with the immunoglobulin G4 (IgG4)-related disease (RD) spectrum. IgG4-RD is a newly recognized immunomediated fibroinflammatory condition characterized by several features: a tendency to form tumefactive lesions at multiple sites, lymphoplasmacytic infiltrate, fibrosis and obliterative phlebitis. Often but not always, the serum IgG4 concentrations are also elevated. Immunohistochemistry for IgG4 is helpful to clinch the diagnosis. Here, we describe a case of 65-year-old male with IgG4-related chronic sclerosing sialadenitis of the s ubmandibular gland. We have discussed the histopathological criteria to diagnose this entity. Wolters Kluwer - Medknow 2020-02 2020-02-28 /pmc/articles/PMC7069128/ /pubmed/32189922 http://dx.doi.org/10.4103/jomfp.JOMFP_83_17 Text en Copyright: © 2020 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gurwale, Sushama Govindrao
Gore, Charusheela Rajesh
Gulati, Ishita
Dey, Indranil
Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity
title Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity
title_full Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity
title_fullStr Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity
title_full_unstemmed Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity
title_short Immunoglobulin G4-related chronic sclerosing sialadenitis: An emerging entity
title_sort immunoglobulin g4-related chronic sclerosing sialadenitis: an emerging entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069128/
https://www.ncbi.nlm.nih.gov/pubmed/32189922
http://dx.doi.org/10.4103/jomfp.JOMFP_83_17
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