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Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer

BACKGROUND: Poly (ADP-ribose) polymerase inhibitors targeting BRCA1/2 mutations are available for treating patients with high-grade serous ovarian cancer. These treatments may be more appropriately directed to patients who might respond if the tumor tissue is additionally tested by next-generation s...

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Detalles Bibliográficos
Autores principales:	Eoh, Kyung Jin, Kim, Hye Min, Lee, Jung-Yun, Kim, Sunghoon, Kim, Sang Wun, Kim, Young Tae, Nam, Eun Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069205/ https://www.ncbi.nlm.nih.gov/pubmed/32164585 http://dx.doi.org/10.1186/s12885-020-6693-y

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