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Targeted cell imaging properties of a deep red luminescent iridium(iii) complex conjugated with a c-Myc signal peptide

A nuclear localisation sequence (NLS) peptide, PAAKRVKLD, derived from the human c-Myc regulator gene, has been functionalised with a long wavelength (λ(ex) = 550 nm; λ(em) = 677 nm) cyclometalated organometallic iridium(iii) complex to give the conjugate Ir-CMYC. Confocal fluorescence microscopy st...

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Detalles Bibliográficos
Autores principales: Day, Adam H., Übler, Martin H., Best, Hannah L., Lloyd-Evans, Emyr, Mart, Robert J., Fallis, Ian A., Allemann, Rudolf K., Al-Wattar, Eman A. H., Keymer, Nathaniel I., Buurma, Niklaas J., Pope, Simon J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069228/
https://www.ncbi.nlm.nih.gov/pubmed/32206278
http://dx.doi.org/10.1039/c9sc05568a