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Pre-existing antitherapeutic antibodies against the Fc region of the hu14.18K322A mAb are associated with outcome in patients with relapsed neuroblastoma

PURPOSE: Patients with cancer receiving tumor-reactive humanized monoclonal antibody (mAb) therapy can develop a human antihuman antibody (HAHA) response against the therapeutic mAb. We evaluated for HAHA in patients with neuroblastoma treated in a phase I study of humanized anti-GD2 mAb (immunoglob...

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Detalles Bibliográficos
Autores principales:	Goldberg, Jacob L, Navid, Fariba, Hank, Jacquelyn A, Erbe, Amy K, Santana, Victor, Gan, Jacek, de Bie, Fenna, Javaid, Amal M, Hoefges, Anna, Merdler, Michael, Carmichael, Lakeesha, Kim, KyungMann, Bishop, Michael W, Meager, Michael M, Gillies, Stephen D, Pandey, Janardan P, Sondel, Paul M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069273/ https://www.ncbi.nlm.nih.gov/pubmed/32169872 http://dx.doi.org/10.1136/jitc-2020-000590

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