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Peritumoral administration of IFNβ upregulated mesenchymal stem cells inhibits tumor growth in an orthotopic, immunocompetent rat glioma model
BACKGROUND: Immunotherapy with IFNβ is a promising strategy for treating malignant glioma. However, systemic administration of IFNβ is inadequate because of low intratumoral concentration and major adverse effects. This study aimed to determine whether mesenchymal stem cells (MSCs) can be used as ce...
Autores principales: | Mao, Jiaji, Cao, Minghui, Zhang, Fang, Zhang, Jingzhong, Duan, Xiaohui, Lu, Liejing, Yang, Zehong, Zhang, Xiang, Zhu, Wangshu, Zhang, Qinyuan, Wang, Zhe, Shen, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069318/ https://www.ncbi.nlm.nih.gov/pubmed/32169868 http://dx.doi.org/10.1136/jitc-2019-000164 |
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